Ֆիզիկայի ֆակուլտետ
Faculty of Physics
The process of training specialists in the field of physics and mathematics began in 1922 in YSU.:
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Evgeny Sh. Mamasakhlinov

Associate Professor | Chair of Molecular Physics
Education
1986: Graduated from Faculty of Physics, Yerevan State University

Academic degree
Dr.Sci. (03.00.02-Biophysics). Thesis: “Spatial and temporal scales in conformational transitions in biopolymers”, 2011, Yerevan State University, Yerevan, Armenia
Candidate of phys.-math. sci. (03.00.02-Biophysics). Thesis: “The helix - coil transition in polypeptides. Microscopic approach”, 1989, Institute of Physics of Georgian Academy of Science, Tbilisi

Professional experience
2006 - present: Prof. of Department of Molecular Physics, Faculty of Physics, YSU.
2006 - 2007: Head of Dept. of Grants, YSU.
1996 - 2006: Associate Prof. of Department of Molecular Physics, Faculty of Physics, YSU.
1992 - 1996: Scientific Researcher of Laboratory of the Physics of Macromolecules Department of Molecular Physics, YSU

Academic courses
"Physics of the Condensed State of Macromolecules" for 4-th year bachelor students, YSU
"Introduction to Non-Equilibrium Thermodynamics" for 1-st year magister students, YSU
"Physics of Biological and Synthetic Polymers" for 2-nd year master students, YSU

Scale of professional interests
RNA and protein folding. Conformational transitions in DNA and DNA condensation. Statistical physics of macromolecules. Non-equilibrium thermodynamics.

Participation in grant projects
1994: RYX000 from International Science Foundation
2002 - 2007: ISTC # A 301.2
2005: 05-ns-molbio-815-503 from ANSEF
2011: PS condmatth 2567 from ANSEF
2012 - 2014: Project ”Equilibrium and non–equilibrium behavior of single– and double–stranded biological molecules” from Volkswagenstiftung
2013: Project ”Dynamics of the self-assembly of DNA-coated carbon nanotubes in polymer matrix” from German Federal Ministry of Education and Research and Ministry of Education and Science RA
2013 - 2015: Kinetics and thermodynamics of translocation of nucleic acids during the sequencing in protein nano – channel

Awards received
President Prize in Natural Sciences for 2013 (26.05.2014)

Languages
Armenian, Russian, English

y.mamasakhlisov@ysu.am

A. Ye. Mamasakhlisov, Ye. Sh. Mamasakhlisov
The conductivity of the monolayer of complexes of DNA with quantum dots in the presence of intercalating ligands (ԴՆԹ-ի կոմպլեքսների քվանտային կետերի հետ մոնոլեյերների հաղորդունակությունը փոխկապակցվող լիգանդների ներկայությամբ)
2019 | Article
ԵՊՀ Գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2019, հ. 53, #3, էջ 203-207
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The double-stranded DNA stability in presence of a flexible polymer
2018 | Article
Journal of biomolecular structure & dynamics. 2018, 36, 1-12 pp.
A. V. Asatryan, A. K. Andriasyan, A. A. Hakobyan, Sh. A. Tonoyan , Ye. Sh. Mamasakhlisov , V. F. Morozov
Straight calculation of helix–coil transition parameters in heteropolymers (Հետերոպոլիմերներում պարույր–կծիկ անցման պարամետրերի ուղիղ հաշվարկ)
2018 | Article
ԵՊՀ գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2018, հ. 52, #1, էջ 47-54
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Theoretical Description of ssDNA Adsorption on Carbon Nanotubes
2018 | Thesis
6th International Iberian Biophysics Congress and X Iberoamerican Congress of Biophysics. 2018, p. 69
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The double-stranded DNA stability in presence of a flexible polymer
2018 | Article
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2018, 36, 1-12 pp.
А. В. Асатрян, А. К. Андриасян, Ш. А. Тоноян , Е. Ш. Мамасахлисов , В. Ф. Морозов
Переход порядок-беспорядок в гетерогенных биологических макромолекулах
2018 | Article
Вестник Российско-Армянского Университета: Физико-математические и естественные науки, 2018, 1, стр. 41-54
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Sh. A. Tonoyan , A. A. Hakobyan, A. K. Andreassian, V. F. Morozov , Y. Sh. Mamasakhlisov
Sensitivity of DNA Sensors in the Presence of Charged Ligands
2018 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences), 2018, Vol. 53, Issue2, 179-186 pp.
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Hrachya Astsatryan, Wahi Narsisian, Eliza Gyulgyulyan, Vardan Baghdasaryan, Armen Poghosyan, Yevgeni Mamasakhlisov , Peter Wittenburg
An integrated web-based interactive data platform for molecular dynamics simulations
2018 | Article
Scalable Computing: Practice and Experience, 2018, Volume 19, Number 2, 131-138 pp.
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Effect of ligands binding on the isotherm of hybridization of the DNA-chip
2017 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences). 2017, 52,2, pp. 180-188
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Fluctuations in order–disorder transitions in the DNA–ligand complexes with various binding mechanisms
2017 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences). 2017, 52, 2, pp. 173-179
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Effect of ligand binding on functionality of DNA field-effect transistor (Լիգանդի կապման ազդեցությունը ԴՆԹ-ի դաշտ-էֆեկտ փոխանցիչի գործառնության վրա)
2017 | Article
ԵՊՀ գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2017, հ. 51, #1, էջ 66–70
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The Helix-Coil Transition the Frames of GMPC. Ligands Effects
2017 | Thesis
International workshop and young scientist school on Critical Phenomena and Phase Transition. 2017, 14-15 pp.
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Constrained Annealing Approach for Order-Disorder Transitions in heterogeneous Macromolecular Systems
2017 | Article
International Workshop and Young Scientist School on Critical Phenomena and Phase Transition. 2017, 20-21 pp.
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Yevgeni Mamasakhlisov , A. Andreassian, A. Hakobyan
Reentrant Melting of Single - Stranded RNA with Quenched Sequence Randomness
2017 | Thesis
International workshop and young scientist school on Critical Phenomena and Phase Transition. 2017, p. 13
Armen Poghosyan, Hrachya Astsatryan, Wahi Narsisian, Yevgeni Mamasakhlisov
On the Performance and Energy Consumption of Molecular Dynamics Applications for Heterogeneous CPU-GPU Platforms Based on Gromacs
2017 | Article
Cybernetics and Information Technologies, 2017, Volume 17, No 5, 68-80 pp.
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Sh. A. Tonoyan , A. V. Asatryan, D. L. Hayrapetyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Possible mechanism of non-monotone behavior of helix-coil transition temperature in two-component solvent
2016 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences). 2016, 51, 1, 93-98 pp.
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Armen T. Karapetian, Zareh A. Grigoryan, Yevgeni Sh. Mamasakhlisov , Mikael V. Minasyants, Poghos O. Vardevanyan
Theoretical treatment of helix-coil transition of complexes DNA with two dofferent ligands having different binding parameters
2016 | Article
Journal of biomolecular structure & dynamic. 2016, 34,1, 198-202 pp.
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A. T. Karapetian, Z. A. Grigoryan, Y. Sh. Mamasakhlisov , M. V. Minasyants, P. O. Vardevanyan
Theoretical treatment of helixcoil transition of complexes DNA with two different ligands having different binding parameters
2015 | Article
J. Biomol. Struct. Dyn., 2015, DOI: 10.1080/07391102.2015.1010584
A. Badasyan, Y. Sh. Mamasakhlisov , R. Podgornik, V. A. Parsegian
Solvent effects in the helix-coil transition model can explain the unusual biophysics of intrinsically disordered proteins
2015 | Article
J. Chem. Phys., 2015, v. 143, 014102(1-7)
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Y. Sh. Mamasakhlisov , S. Bellucci, Sh. Hayryan, H. Caturyan, Z. Grigoryan, C.-K. Hu
Collapse and hybridization of RNA: view from replica technique approach
2015 | Article
Europhys. J. E, 2015, v. 38, 100 p.(1-9)
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Generalized Model of Polypeptide Chainfor Helix-Coil Transition in Two-component Solvent
2015 | Book
J. Contemp. Phys. 50, N 4, 375 - 380 pp.(2015)
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Y. Mamasakhlisov , Sh. Hayryan, V. Morozov , C.-K. Hu
Kinetics of the long ssRNA: Steady state
2014 | Article
Europhys. Lett., 2014, v. 106, 48007(1-6)
G. N. Hayrapetyan, F. Iannelli, J. Lekscha, V. F. Morozov , R. R. Netz, Y. Sh. Mamasakhlisov
Cold melting of RNA with quenched sequence randomness
2014 | Article
Phys. Rev. Lett., 2014, v. 113, 068101(1-5)
A. V. Badasyan, Sh. A. Tonoyan , A. Giacometti, R. Podgornik, V. A. Parsegian, Y. Sh. Mamasakhlisov , V. F. Morozov
Unified description of solvent effects in the helix-coil transition
2014 | Article
Phys. Rev. E 89 022723( 2014)
Helix-coil transition in biopolymers with multicomponent heterogeneity of energy and number of conformations
2014 | Article
J. Contemp. Phys. 49, N 3, 132 (2014)
G. N. Hayrapetyan, Y. Sh. Mamasakhlisov , V. F. Morozov , V. V. Papoyan, V. B. Priezzhev
Two-dimensional random walk and critical behavior of double-strand DNA
2013 | Article
J. Phys. A: Math. Theor., 2013, v. 46, 035001(1-9)
A. Badasyan, A. Giacometti, R. Podgornik, Y. Mamasakhlisov , V. Morozov
Helix-coil transition in terms of Potts-like spins
2013 | Article
Eur. Phys. J. E, 2013, v. 36, 46, DOI 10.1140/epje/i2013-13046-7
G. N. Hayrapetyan, H. L. Tsaturyan, Sh. A. Tonoyan , Y. Sh. Mamasakhlisov
Thermodynamics of single-stranded RNA with random sequence: Constrained annealing approach
2013 | Article
J. Contemp. Phys. 48, N 2, 98 (2013)
On the theory of helix-coil transition in heterogeneous biopolymers. Constrained annealing method
2013 | Article
J. Contemp. Phys. 48, N 5, 236 (2013)
Y. Sh. Mamasakhlisov , Sh. Hayryan, C.-K. Hu
Long charged macromolecule in an entropic trap with rough surfaces
2012 | Article
Phys. Rev. E, 2012, v. 86, 051904(1-5)
A. V.Badasyan, S. A. Tonoyan , A. Giacometti, R. Podgornik, V. A. Parsegian, Y. Sh. Mamasakhlisov , V. F. Morozov
Osmotic pressure induced coupling between cooperativity and stability of a helix-coil transition
2012 | Article
Phys. Rev. Lett. 109, 068101 (2012)
A. V. Badasyan, Sh. A. Tonoyan , Y. Sh. Mamasakhlisov , A. Giacometti, A. S. Benight, V. F. Morozov
Competition for hydrogen-bond formation in the helix-coil transition and protein folding
2011 | Article
Phys. Rev. E 83 051903 (2011)
S. Bellucci, Y. Mamasakhlisov , A. Nersessian
External field influence on semiflexible macromolecules: geometric coupling
2011 | Article
Mod. Phys. Lett. B, 2011, v. 25, 1809-1819
Differential Geometry in DNA molecules
2011 | Article
Nanoscience and Nanotech. Lett., 2011, v. 3, 922-926
A. V. Badasyan, A. Giacometti, Y. Sh. Mamasakhlisov , V. F. Morozov , A. S. Benight
Microscopic formulation of the Zimm-Bragg model for the helix-coil transition
2010 | Article
Phys. Rev. E, 2010, v. 81, 021921(1-4)
Different stability of RNA secondary and tertiary structures (ՌՆԹ-ի երկրորդային և երրորդային կառուցվածքների տարբեր կայունություններ)
2009 | Article
ԵՊՀ Գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2009, #3, էջ 55–57
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A. V. Badasyan, G. N. Hayrapetyan, Sh. A.Tonoyan , Y. Sh.Mamasakhlisov , A. S. Benight, V. F. Morozov
Intersegment interactions and helix-coil transition within the Generalized Model of Polypeptide Chains (GMPC) approach
2009 | Article
J. Chem. Phys., 2009, v. 131, 115104
Y. Sh. Mamasakhlisov , B.A. Todd, A.V. Badasyan, A.V. Mkrtchyan, V.F. Morozov , V. A. Parsegian
DNA stretching and Multivalent-Cation-Induced Condensation
2009 | Article
Phys. Rev. E, 2009,v. 80, 031915(1-9)
A. V. Badasyan, Sh.A. Tonoyan , A.V. Tsarukyan, Y. Sh. Mamasakhlisov , A.S. Benight, V.F. Morozov
Two Scale Generalized Model of Polypeptide Chain
2008 | Article
J. Chem. Phys.128,195101 (2008)
Y. Sh. Mamasakhlisov , A. Naji, R. Podgornik
Partially Annealed Disorder and Collapse of Like-Charged Macroions
2008 | Article
J. Stat. Phys., 2008, v. 133, 659-681
A. V. Tsarukyan, Sh. A. Tonoyan , G. N. Hayrapetyan, I. V. Baghdyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Helix-Coil Transition in the Case of Interaction Between Two Chains
2008 | Article
J. Contemp. Phys. 43, N 5, 254 (2008)
Sh. A. Tonoyan , G. N. Hayrapetyan, A. V. Tsarukyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Generalized Model of Polypeptide Chain With Limitation on the Length of Helical Fractions
2008 | Article
J. Contemp. Phys. 43, N 4, 203 (2008)
Hybridization kinetics of DNA short fragments
2008 | Article
Electronic Journal of Natural Sciences., 2008, V. 2 (11), 3, Р. 3-6
Stochastic model of adsorption of particles on macromolecules at an arbitrary filling
2008 | Article
J. Contemp. Phys., 2008, V. 43, P.48-53
A.V. Grigoryan, E.Sh. Mamasakhlisov , T.Yu. Buryakina, A.V. Tsarukyan , A.S. Benight, V. F. Morozov
Stacking heterogeneity: A model for the sequence dependent melting cooperativity of duplex DNA
2007 | Article
J. Chem. Phys., 2007, v. 126, 165101 (1-9)
Y. Sh. Mamasakhlisov , Sh.A. Hayryan, V. F. Morozov , C.-K. Hu
RNA Folding in the Presence of Counterions
2007 | Article
Phys. Rev. E, 2007, v. 75, 061907 (1-10)
Y. Sh. Mamasakhlisov , Sh.A. Hayryan, C.K. Hu
Random Sequences with Power-law Correlations Exhibit Protein-like Behavior
2007 | Article
J. Chem. Phys., 2007, v.126, 145103 (1-10)
Complexes of bovine serum albumin with water-soluble Cu and Co containing cationic meso-tetra-(4-N-oxyethylpyridyl)-porphyrins
2007 | Article
J. Porphyrins Phthalocyanines, V 11, N 7, pp.475-480 (2007)
Sh. A. Tonoyan , T. Yu. Buryakina, A. V. Tsarukyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Generalized model of polypeptide chain with two-scale interactions
2007 | Article
J.Contemp. Phys. 42, N6, 309 (2007)
A. V. Tsarukyan, Sh. A. Tonoyan , A. V. Badasyan, A. V. Grigoryan, E. Sh. Mamasakhlisov , V. F. Morozov
Order parameters of helix-coil transition in biopolymers
2006 | Article
J. Contemp.Phys., 41, N 1, 54 (2006)
Е.Ш. Мамасахлисов , А.В. Бадасян, В.Ф. Морозов , А.В. Григорян, A.В. Царукян
Влияние конкурентного и не конкурентного растворителя на переход спираль-клубок в биополимерах
2005 | Article
Известия НАН Армении, Физика, 2005, т. 40, N 2, сс. 111-115
A.V. Tsarukyan, Sh. Tonoyan, A.V. Badasyan, A.V. Grigoryan, E. Sh. Mamasakhlisov , V.F. Morozov
The helix-coil transition and definition of the order parameter in the scope of the generalized model of polypeptide chains
2005 | Article
NAS RA, Electronic Journal of Natural Sciences, 2005, v. 2, pp. 8-11
V.F. Morozov , A.V. Badasyan, A.V. Grigoryan, E.Sh. Mamasahlisov , Sh.A. Hayryan, C.-K. Hu
Helix-Coil Transition in Closed Circular DNA
2005 | Article
Physica A, 2005, v. 348C, pp. 327-338
V. F. Morozov , A. V. Badasyan, A. V. Grigoryan, M. A. Sahakyan, E. Sh. Mamasakhlisov
Stacking Decreases the Cooperativity of Melting of Homopolymeric DNA
2005 | Article
Modern Physics Letters B, v.19, 2005, pp. 79-83
A.V. Grigoryan, A.V. Badasyan, V.F. Morozov , E. Sh.Mamasakhlisov
The invariance of order parameter and temperature redefinition in helix-coil transition of circular closed DNA
2005 | Thesis
Physics of Atomic Nuclei, 2005, v.10, p. 1748
A.V. Badasyan, A.V. Grigoryan, E.Sh. Mamasakhlisov , V.F. Morozov
Order-disorder transition in one-dimensional system with disorder in composition
2005 | Article
Physics of Atomic Nuclei, 2005, v.11, p. 1984
A.V. Badasyan, A.V. Grigoryan, E.Sh. Mamasakhlisov , A.S. Benight, V.F. Morozov
The helix-coil transition in heterogeneous double stranded DNA: Microcanonical method
2005 | Article
J. Chem. Phys., 2005, 1v. 123, 194701 (1-6)
E. Sh. Mamasakhlisov , A. V. Badasyan, A. V. Tsarukyan, A. V. Grigoryan , V. F. Morozov
The generalized model of polypeptide chain describing the helix-coil transition in biopolymers
2005 | Article
Preprint of International Centre for Theoretical Physics, IC/2005/037 www.ictp.it/~pub_off
A. Tsarukyan, Sh. Tonoyan , A. Badasyan, A. Grigoryan, E. Mamasakhlisov , V. Morozov
The Helix Coil Transition and Definition of the Order Parameter in the Scope of the GMPC
2005 | Article
Electronic Journal of Natural Sciences (Biophysics) 2, 5 (2005)
А.В. Бадасян, А.В. Григорян, Е.Ш. Мамасахлисов , В.Ф. Морозов
Анализ перехода спираль-клубок в кольцевой замкнутой ДНК на основе статистической модели
2004 | Article
Известия НАН Армении, Физика, 2004, т. 39, N 4, сс. 265-270
Some dynamic properties of random heteropolymers with correlation in sequence
2001 | Article
Modern Problems of Cellular and Molecular Biophysics, Noyan Tapan, Yerevan, 2001, pp. 209-219
E.Sh. Mamasakhlisov , V.F. Morozov , Sh.A. Hayryan, C.-K. Hu
Microscopical Approach to the Helix- Coil Transition in DNA
2000 | Article
Physica A, 2000, v.281, pp. 51-59
Haroutiunian S.G. , Dalyan Y.B. , Morozov V.F. , Mamasachlissov Eu.Sh. , Shahinian M.S., Akhrem A.A., Lando D.Yu., Messori L., Orioli P.
Influence of cis- and trans-diamminedichloroplatinum(II) binding on the helix-coil transition of DNAs with different GC-content
1998 | Article
Inorganica Chimica Acta, 1998, 275-276, 510-514
The Lack of Long - Range Correlations is a Necessary Conditions of the Biologically Functional Protein
1997 | Article
J. Phys. A (Math. & Gen.) 1997, v.30, pp. 7765 – 7772
Haroutiunian S.G , Mamasakhlissov Eu.Sh. , Dalyan Y.B. , Morozov V.F. , Khachikyan R.E., Vardevanyan P.O., Karapetyan A.T, P.Oriօli, B.Bruni
The modification of the spatial structure of DNA in its complexes with cis-DDP
1997 | Article
Biophysics 1997, 42, 372-377. (in Russian)
Арутюнян С.Г., Мамасахлисов Е.Ш. , Морозов В.Ф. , Далян Е.Б. , Хачикян Р.Э., Вардеванян П.О. , Карапетян А.Т., Ориоли П., Бруни Б.
Модификация пространственной структуры ДНК в комплексе с цис-платиной
1997 | Article
Биофизика, 1997, 42(2), с.372-377
Helix-coil transition in polypeptides. A Microscopic approach II
1995 | Article
Biopolymers, 1995, v.35 N 1, pp. 75-84
Sh.A.Hairyan, N.S.Ananikyan, E.Sh.Mamasahlisov , V.F. Morozov
Helix-coil transition in polypeptides. Microscopic approach
1990 | Article
Biopolymers, 1990, v.30, NN 3/4, pp. 357-367
V. F. Morozov , Ye. Sh. Mamasakhlissov , D. M. Minasian, V. M. Aslanian
Построение статистической суммы линейной макромолекулярной системы (Գծային մակրոմոլեկուլային համակարգի ստատիստիկական գումարի կառուցումը)
1988 | Article
ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 1988, #3, էջ 162-164 (ռուսերեն)
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Размеры полипептидных цепей при переходе спираль–клубок. Макроскопическая теория (Պոլիպեպտիդային շղթաների չափսերը սպիրալ-կծիկ անցման մամանակ։ Միկրոսկոպիկ տեսություն)
1987 | Article
ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 1987, #3, էջ 51-54 (ռուսերեն)
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