Ֆիզիկայի ֆակուլտետ
Faculty of Physics
The process of training specialists in the field of physics and mathematics began in 1922 in YSU.:
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Gayane V. Ananyan

Associate Professor | Chair of Molecular Physics
Education
1983: Graduated from Faculty of Physics, Yerevan State University

Academic degree
Candidate of phys. - math. sci. (03.00.02-Biophysics) - “The role of central metal in complexation of water-soluble metalloporphyrins with DNA”, 2007, Yerevan State University.

Professional experience
1983 - 2002: Lab. Assistant of Department of Molecular Physics, Faculty of Physics, YSU.
2002 - 2007: Junior Scientific Researcher of Department of Molecular Physics, Faculty of Physics, YSU.
2007 - 2009: Senior Scientific Researcher of laboratory “Structural Biophysics” YSU.
2009: Senior Scientific Researcher of laboratory “Structural Biophysics” YSU.

Academic courses
"Molecular Physics" practice for 1-th year bachelor students, YSU,
"Investigation Methods of Biopolymers" for 1-th year master students, YSU.

Scale of professional interests
The investigation of thermostability and conformation of DNA at complexation with potential antitumor (Pt - complexes, porphyrins and metalloporphyrins) preparations in different condition (pH, ioning strength).

Participation in grant projects
2015 - 2017: 5T-1F054
2003 - 2007: ISTC #A-301.2
2011 - 2013: 11РБ-017
2013 - 2015: 13-1F094

Languages
Armenian, Russian, English

angay@ysu.am

Latest Publications (59)
Influence of zinc oxide nanoparticles on bilayer lipid membrane properties (Ցինկի օքսիդի նանոմասնիկների ազդեցությունը երկշերտ լիպիդային թաղանթների հատկությունների վրա)
2019 | Article
ԵՊՀ Գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2019, հ. 53, #3, էջ 208-213
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Development of viscometric methods for studying the interaction of porphyrins with DNA
2019 | Article
Journal of biomolecular structure & dynamics. 2019, 20, pp. 1-6
Molecular alterations in DNA under UV-irradiation
2019 | Thesis
Albany 2019: The 20th Conversation. 2019, p. 86
Changes in the stability and conductivity of BLM in the presence of zinc oxide nanoparticles
2019 | Thesis
Albany 2019: The 20th Conversation. 2019, pp. 86-87
The effect of porphyrins configuration on the hydrodynamic behavior of DNA solutions
2019 | Thesis
Albany 2019: The 20th Conversation. 2019, pp. 84-85
Development of viscometric methods for studying the interaction of various porphyrins with DNA. Part IV: Meso-tetra-(4N-allylpyridyl) porphyrin and its Cu-, Coand Zn-containing derivatives
2018 | Article
Journal of Porphyrins and Phthalocyanines. 2018, 22, 1-8 pp.
Influence of nanoparticles of CuO on the stability and conductivity of BLM (Պղնձի օքսիդի նանոմասնիկների ազդեցությունը երկշերտ լիպիդային թաղանթների կայունության և հաղորդականության վրա)
2018 | Article
ԵՊՀ գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2018, հ. 52, #1, էջ 41-46
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Influence of structural features of porphyrins on their ability to effect on DNA
2017 | Article
International Conference On Nanomedicine And Nanobiotechnology:ICANON 2017. p. 1
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Interaction of Meso-tetra-(4N-allylpyridyl) porphyrin and its Cu-, Co- and Zn- containing derivatives with DNA
2017 | Article
Biological Journal of Armenia. 2017, 4 (69), 84-93 pp.
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Development of viscometric methods for studying the interaction of various porphyrins with DNA. Part III: Meso-tetra-(3N-alylpyridyl) porphyrin and its Cu-, Co- and Zn- containing derivatives
2017 | Article
Journal of Porphyrins and Phthalocyanines. 2017, 21, pp. 110-115
Плавление ДНК опуxоленоcящиx кpыc, леченыx мезо-тетpа(4-n-гидpокcиэтилпиpидил)поpфиpином и его AG-, ZN-, CO-пpоизводными
2017 | Article
Биофизика. 2017, 62, 3, стр. 458–463
Application of viscometric methods for studying the interaction of various porphyrins with DNA
2016 | Thesis
Albany 2015.19th Conversation. 2016, p. 88
Карапетян Н. Г., Ананян Г. В. , Далян Е. Б., Арутюнян С. Г.
Лечение опухоленосящих крыс мезо-тетра(4N-гидроксиэтилпиридил) порфиринами H2TOEtPyP4 и AgTOEtPyP4
2016 | Thesis
Биомедицина–2016. p. 106
Development of viscometric methods for studying the interaction of various porphyrins with DNA. Part II: Meso-tetra-(3N-hydroxyethylpyridyl) porphyrin and its Ni-, Cu-, Co- and Zn- containing derivatives
2016 | Article
Journal of Porphyrins and Phthalocyanines, 2016, 20, 1-7 pp.
Application of viscometric methods for studying the interaction of various porphyrins with DNA
2016 | Thesis
Journal of biomolecular structure & dynamics. 2016, 34, p. 136
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Development of viscometric methods for studying the interaction of various porphyrins with DNA. Part II: Meso-tetra-(3N-hydroxyethylpyridyl) porphyrin and its Ni-, Cu-, Co- and Zn- containing derivatives
2016 | Article
Journal of Porphyrins and Phthalocyanines, 2016, 20, 766-772 pp.
The features of complex formation of poly(dI-dC)2with porphyrins
2015 | Thesis
Albany 2015:19th Conversation Journal of Biomolecular Structure and Dynamics, V.33, S.1., 2015, p. 85. DOI:10.1080/07391102.2015.1032765
Effect of configuration of porphyrin molecule on the complexation with DNA. DOM2015
2015 | Thesis
Int.Conf. Armenia, Yerevan, 24-30september, 2015, p. 92-93
Application of viscometric methods for studying the interaction of various porphyrins with DNA
2015 | Thesis
Journal of Biomolecular Structure and Dynamic. Vol. 33, No. 136, p. 88-89, 2015
Development of viscometric methods for studying the interaction of various porphyrins with DNA
2014 | Article
Part I: meso-tetra-(4N-hydroxyethylpyridyl) porphyrin and its Ni-, Cu-, Co- and Zn- containing derivatives. Journal of Porphyrins and Phthalocyanines 2014 18:07, 594-599. DOI: 10.1142/S1088424614500357
Development of viscometric methods for studying the interaction of various porphyrins with DNA. Part I: meso-tetra-(4N-hydroxyethylpyridyl) porphyrin
2014 | Article
J. Porphyrins and Phthalocyanines, N 18, p. 594–599, (2014)
Characterization and differentiation of binding modes of water-soluble porphyrins at complexation with DNA
2013 | Thesis
Journal of Biomolecular Structure and Dynamics, 2013. v. 31, # S1, 56
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Characterization of binding modes of water-soluble porphyrins at complexation with DNA in presence of hard peripheral radicals
2013 | Article
Int. Conf. Phys. Concepts of Nucl. Acid Struct. And Behavior Fuded by Volkswagenstiftung, June 27-29, 2013, pp. 32-34
Comparative study of complexes H2TOEPyP4 and Cu(II) TOEPyP4 porphyrins with DNA modified by cisDDP
2012 | Thesis
Perspectives for development of molecular and cellular biology III, Proceedings. Sept. 26-29, p.130-136, 2012
The stability of DNA-porphyrin complexes in the presence of Mn(II) ions
2011 | Article
Biophys. Chem. 156 (1) pp. 96-101 (2011)
The Stability of DNA-Porphyrin Complexes in the Ppresence of Mn(II) ions
2010 | Thesis
International Symposium “Solvation and Ionic Effects in Biomolecules: Theory to Experiment”, Tsakhkadzor, Armenia, Book of abstracts, p. 37 (2010)
L. H. Demirkhanyan, M. A. Melnikova-Sharova, I. G. Artsruni, K. S. Matinyan, G. V. Ananyan , E. S. Gevorgyan, E. S. Tissue
Tissue-Specific Changes in DNA Melting profiles Induced by Cisplatin
2010 | Thesis
Int.Symposium "Solvation and Ionic Effects in Biomolecules: Theory to Experiment", Armenia, Tsakhkadzor, May 17-21 2010, p. 55
DNA damage and anti-tumor activity induced by Zn, Ag and Co containing meso-tetra(4-N-oxyethylpyridyl)porphyrins in vivo
2010 | Article
J. Porphyrins Phthalocyanines, 2010, v. 14, p. 349–353
The comparative study of CuTAlPyP(4) and CоTAlPyP(4) porphyrins with DNA
2009 | Thesis
Int.Conf. Albany, 16th Conversation Issue, June 2009, v.26, #6, p. 901-902
The Comparative Study of CuTButPyP4 and CoTButPyP4 Porphyrins with DNA
2009 | Thesis
Int.Conf. “Biotechnology and health-3” & DAAD Alumni seminar. Yerevan, Armenia, October 15-17, 2009, p. 122
Influence of ionic strength on interaction of Co(II)-containing porphyrins with DNA
2008 | Thesis
The Young Scientists Conference "Perspectives for Development of Molecular and Cellular Biology". Yerevan, Armenia, 2008, p. 17
«Կենսապոլիմերների ուսումնասիրման մեթոդներ»
2008 | Book
Ուսումնամեթոդական ձեռնարկ: Երևան, 2008, 85 էջ
Комплексообразование H2TAlPyP4 и CoTAlPyP4 порфиринов с ДНК
2008 | Thesis
Межд.конф. посвященная 100-летия со дня рождения НАН РА А.Б. Налбандяна “Современные проблемы химической физики”. Yerevan, Armenia, 21-24 октября 2008г. с.110
Cisplatin Recovers Glucocorticoid-Induced DNA Condensation in Rat Liver Nuclei
2008 | Thesis
Proceedings of International Conference “Frontiers in Cancer Prevention Research”, Washington, DC, 2008, p.146
The Influence of ionic strength on the interactionof Porphyrins with DNA
2007 | Article
Vestnik SPSU, V 4, N2, pp. 48-52 (2007)
Interaction of Mn(III)-containing porphyrins with DNA
2007 | Thesis
Int.Conf. “New Polymers and Radioprotectors for Biology and Medicine”. Yerevan, Armenia, 8-10 October, p.11-12, 2007
B Сравнительное исследование параметров плавления ДНК в тканях здоровой, опухоленосящей и леченной порфирином мыши, в присутствии Mn2+
2007 | Thesis
Int.Symposium under the auspieces of UNESCO dedicated to the centenary of Academician N.M.Sissakian’s birth. "Problems of biochemistry, molecular, radiation biology and genetics". Yerevan-Ashtarak, 2007, p.55,
The influence of ionic strength on the binding of porphyrins with DNA
2007 | Article
Vestnik SPbSU.Ser.4 Physics, Chemistry, No. 2, p.48-52, 2007
Structural features of the Tumor’s DNA on the presence of AgT4OEPyP
2007 | Article
Vestnik SPbSU.Ser.4 Physics, Chemistry, 2007, #2, 53-57 (in Russian)
Влияние боковых групп порфиринов на их взаимодействие с ДНК (ԴՆԹ-ի հետ պորֆիրինների փոխազդեցության վրա նրանց կողմնային խմբերի ազդեցությունը)
2006 | Article
ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 2006, #3, էջ 40-45 (ռուսերեն)
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Влияние AgT4OEPyP на термодинамические особенности опухолевой ДНК
2006 | Thesis
Конф. “Современные проблемы молекулярной биофизики”, Санкт-Петербург 15-16 июня, 2006. с.37
Interaction of Porphyrins with DNA. Effect of Central metal and Peripheral Substituents
2006 | Thesis
XIII Symposium of intermolecular interaction and conformations of molecules, Saint -Petersburg, Russia, book of Abstract, p.181 (2006)
Далян Е.Б. , Алоян Л.Р. , Ананян Г.В. , Варданян В.И., Казарян А.А
Взаимодействие порфиринов с ДНК. Эффект центрального металла и бокового радикала
2006 | Thesis
XIII Симпозиум по межмолекулярному взаимодействию и конформациям молекул. Санкт-Петербург 19-23 июня, 2006, с. 181
Взаимодействие порфиринов с ДНК. Эффект ионной силы
2006 | Thesis
Конф. "Современные проблемы молекулярной биофизики". Санкт-Петербург 15-16 июня, с. 31, 2006
Features of Ni-containing porphyrins interaction with DNA
2006 | Article
Vestnik IAELPS, 2006, v.11, # 8, i.2, p.244-247,
The Influence of peripheral substituents on Interaction of porphyrins with DNA
2006 | Article
Scientific Notes of YSU, 3, pp. 40-45 (2006)
Interaction of Co-containing meso-tetra-(N-pyridil) porphyrins with DNA
2005 | Thesis
Int. Symposium on Hydration and Thermodynamics of Molecular Recognition, Tsakhkadzor, Armenia, Mar. 1-5, Book of Abstracts, 2005, p.54
Dalyan Y. B. , Ananyan G. V. , Ghazaryan A.A., Aloyan L.R. , Vardanyan V.I
Interaction of new porphyrin drugs with DNA
2005 | Thesis
The SECOND Int.Conf. “Modern Problems of Genetics, Radiobiology, Radioecology and evolution” dedicated to N.W.Timofeev-Ressovsky, Yerevan, 8-11 Sept,2005, p.58.
Viscometric investigation of interaction of some porphyrins with DNA
2005 | Thesis
International Symposium on HTMR-2005, Tsakhkadzor, Armenia, Mar. 1-5, 2005, p.59
Binding of New Meso-Tetra-(3N-Pyridil) Porphyrins to DNA
2003 | Thesis
HUPO 2nd Annual and IUBMB XIX World Congress, October 8-11, Monreal.Molecular and Cellular Proteomics, 2003. v.2, # 9, p.972
Y. B. Dalyan , S. G. Haroutiunian , G. V. Ananyan , V. I. Vardanyan, D. Y. Lando, V. N. Madakyan, R. K. Kazaryan, L. Messori, P.L. Orioli, A. S. Benight
Interactions of Meso-tetra-(4-N-oxyethylpyridyl) Porphyrin, Its 3-N Analog and Their Metallocomplexes with Duplex DNA
2001 | Article
Journal of Biomol. Structure & Dynamics, 2001, v. 18, 677-687
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Комплексообразование металлопорфиринов с ДНК. Эффект центрального металла
2001 | Thesis
II Межд. Симпозиум “Проблемы биохимии, радиационной и космической биологии” посвященной памяти акад. Н.М.Сисакяна. Москва, Дубна, 29-31 мая 2001, Тезисы докладов, с. 74
E. S. Gevorgian , Yu. S. Babayan, L. H. Demirkhanian, G. V. Ananian
Действие гидрокортизона и инсулина на положительную эллиптичность хроматина клеток печени крысы (Հիդրոկարտիզոնի և ինսուլինի ազդեցությունը առնետի լյարդի բջիջներից անջատված քրոմատինի դրական էլիպտականոթյան վրա)
2001 | Article
ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 2001, #1, էջ 86-89 (ռուսերեն)
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The structural peculiarities of some DNA – porphyrin complexes
2000 | Thesis
Int. Conf.DNA Conformation, Modification and Recognition in Biomedicine, 2000, Jule 2-5 Brno, Chech. Republic, Book of Abstracts, p.76
Dalyan Y. B. , Haroutiunian S. G. , Ananyan G. V. , Sahakyan L.A, Madakyan V. N, Kazaryan R. K.
The structural properties of DNA–Metalloporphyrin complexes
1999 | Thesis
5-th Int. Symp. On Applied Bioinorganic Chemistry (5ISASC), 1999, 13-17 April, Corfu, Greece, Book of Abstracts, p.281
Конформационные особенности ДНК в водных растворах некоторых аминокислот цвиттерионного типа.
1986 | Thesis
II Республиканская конференция, посвященная проблемам физико-химической биологии. Ереван 1986
Асланян В.М., Арутюнян С.Г. , Далян Е.Б. , Бабаян Ю.С., Ананян Г.В. , Погосян М.К.
Конформационные превращения и стабильность ДНК в присутствии низкомолекулярных лигандов
1985 | Article
Межвузовский сборник научных трудов "Физика", Изд. ЕГУ, 1985, вып.5, стр.173-183
Babayan Yu. S., Aslanian L. L., Ananyan G. V. , Garibyan J. V.
Phosphemide influence in combination with dexametasone on the structure of sarcoma 45 DNA
1985 | Article
Biophysics, ХХХ, 3, pp.414-417, 1985(in Russian)
Асланян В.М., Бабаян Ю.С., Асланян Л.Л., Ананян Г.В , Казарян Р.С.
Влияние противоопухолевых препаратов алкилирующего типа на структуру опухолевой (саркома 45) ДНК
1984 | Thesis
V Всесоюзная конференция по спектроскопии биополимеров.Харьков тезисы докладов, 1984, 2-4 октября, с. 9-10