Nikolay V. Avtandilyan
Biography
Education
2004 - 2008: Yerevan State University, Faculty of Biology, Department of Biochemistry, BSc.
2008 - 2010: YSU, Department of Biochemistry, MSc.
2010 - 2013: PhD at the Department of Biochemistry, YSU, Yerevan, Armenia

Scientific degree
PhD in Biological Science, “The role of ureotelic and nonureotelic arginases in polyamine biosynthesis”, YSU, Faculty of Biology, Yerevan Armenia

Work experience
2013 - 2014: Senior laboratory assistant at the Department of Biochemistry of Yerevan State University, Yerevan, Armenia.
2015 - 2016: Head of Educational Laboratory, Department of Biochemistry, YSU.
2014 - till now: Junior researcher at the Department of Biochemistry of Yerevan State University, Yerevan, Armenia.

Scientific interests
Biochemistry, enzymology, biomedicine, Cancer biochemistry

Participation in grant projects (present and past)
2012: Travel grant, FEBS Sofia “School of Protein Science: Structure and Dynamics of Biological Macromolecules”, September, Bulgaria.
2016 - 2018: Grant from Ministry of Education and Science of Armenia, State committee of science, the research project № 16YR-1F023 “Arginase and nitric oxide synthase: old enzymes with new perspectives in breast anticancer therapy”. Head of Scientific Group.

Professional Membership
Member of Council of “Young Biologists Association” NGO.
Member of Armenian Association of Biochemists (Federation of European Biochemical Societies) NGO.

Languages
Armenian (native), Russian (Advanced), English (Upper intermediate)

nv.avtandilyan@ysu.am

Nikolay V. Avtandilyan

Assistant | Faculty of Biology - Chair of Biochemistry, Microbiology and Biotechnology
 
 

Article

S. V. Marutyan, G. A. Petrosyan, A. R. Muradyan, L. A. Marutyan, S. A. Marutyan, N. V. Avtandilyan

Կրծքագեղձի և լյարդի ընդհանուր և միտոքոնդրիումային ԱԵՖ-ազային ակտիվության փոփոխությունը կրծքագեղձի քաղցկեղով հիվանդ առնետների մոտ | ԵՊՀ Գիտական տեղեկագիր: Քիմիա և կենսաբանություն, 2022, հ. 56, #2, էջ 151-160 |

N. Avtandilyan, H. Javrushyan, M. Ginovyan, A. Trchounian

New Therapeutic Approaches In Breast Anticancer Treatment Using Armenian Herbal Extracts | Biological Journal of Armenia, 2021, N 1 (73), p. 32-38

N. Avtandilyan, H. Javrushyan, A. Trchounian

The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats | Respiratory Physiology & Neurobiology, 2021, 285, 103598

Nikolay Avtandilyan, Hayarpi Javrushyan, Anna Karapetyan, Armen Trchounian

Inhibition of Tumor Progression by NG-Nitro-L-arginine Methyl Ester in 7,12- dimethylbenz(a)anthracene Induced Breast Cancer: Nitric Oxide Synthase Inhibition as an Antitumor Prevention | Journal of mammary gland biology and neoplasia. 2019, Volume 24, Issue 2, pp. 1-11 |

G. Petrosyan, N. Avtandilyan, H. Javrushyan, A. Trchounian

Arginase is an enzyme with real tricks in antitumor treatment of 7,12-dimethylbenz(a) anthracene induced breast cancer in rats | The 43rd FEBS Congress "Biochemistry Forever". 2018, 385-386 pp. |

Nikolay Avtandilyan, Hayarpi Javrushyan, Gayane Petrosyan, Armen Trchounian

The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer | BioMed Research International. 2018, Volume 2018, 8696923, 9 p.

H. Javrushyan, N. Avtandilyan, A. Mamikonyan, A. Trchounian

The change of polyamines and nitric oxide quantities in human blood serum of prostate and bladder cancer | Biological Journal of Armenia. 2017, 69, 1, 125-132 pp. |

Mariam Sargsyan, Hermine Gevorgyan, Hermine Gevorgyan, Susanna Karapetyan

Changes of arginase activity and arginase isoenzyme spectrum in human serum during different stages of breast cancer before surgery and after chemotherapy | ԵՊՀ ՈՒԳԸ գիտական հոդվածների ժողովածու: 2017, 1.5 (22), էջ 176-183 |

Avtandilyan N. V., Karapetyan S. A., Alexanyan K. A.

The change of arginase activity in blood serum during breast and prostate cancers | Electronic journal of natural sciences, 2016, 1 (26), 12-14 pp. |

Avtandilyan N. V., Karapetyan S. A., Aleksanyan K. A.

The relationship between arginase activity and change of polyamines quantity in human blood serum during breast cancer | Biological Journal of Armenia, 2016, 2 (68), 92-99 pp. |

Մարիամ Սարգսյան, Նիկոլայ Ավթանդիլյան, Սուսաննա Կարապետյան

Պոլիամինների քանակության փոփոխության ուսումնասիրումը լյարդի արգինազի իզոֆերմենտների արգելակման ժամանակ | ԵՊՀ ՈՒԳԸ գիտական հոդվածների ժողովածու, 2015, 1.1 (4), բնական գիտություններ, էջ 75-81 |

Avtandilyan N.V., Karapetyan S. A.

Relationship between liver polyamines quantity and arginase isoenzymes activity after arginase inhibition by NG-hydroxy-L-arginine | National Academy of Sciences of RA, Electronic Journal of Natural Sciences, 1 (24), 2015, pp. 3-6 |

Avtandilyan N. V., Karapetyan S. A., Aleksanyan K. A.

The relationship of blood serum arginase activity and polyamines quantity during human breast cancer | The New Armenian Medical journal. 2015, Vol.9, N, 10 - 10 pp. |
 

Thesis

A. Mamikonyan, H. Javrushyan, N. Avtandilyan, Р. Арутюнян, A. Trchounian

Suppression of tumor progression by arginaseand NO-synthase combined inhibition in7,12- dimethylbenz(a)anthracene-inducedbreast cance r in rats | FEBS Open Bio, 45th FEBS Congress, Molecules of Life: Toward New Horizons, 03-08.07.2021, p. 413, Slovenia

N. Avtandilyan, A. Mamikonyan, H. Javrushyan, A. Trchounian

Suppression of tumor progression by arginaseand NO-synthase combined inhibition in7,12- dimethylbenz(a)anthracene-inducedbreast cance r in rats | FEBS Open Bio, 45th FEBS Congress, Molecules of Life: Toward New Horizons, 03-08.07.2021, p. 413, Slovenia

N. Avtandilyan, G. Petrosyan, A. Trchounian

Oxidative stress in the 7,12-dimethylbenz[a] anthracene rat model of breast cancer: suppression by a NO-synthase inhibitor NG- nitro-L-arginine methyl ester | The 44th FEBS Congress “From molecules to living systems”. 2019, pp. 341-341 |

Mamikonyan A., Avtandilyan N., Javrushyan H., Trchounian A.

Inhibition of nos activity as an effective anticancer therapy against 7,12-DMBA rat model of breast cancer | International conference „Smart Bio“. 2018, p. 114 |

N. Avtandilyan, A. Trchounian

The potential therapeutic effect of nor-NOHA and L-NAME in breast cancer treatment | FEBS workshop on Emerging issues of breast cancer research: tumour heterogeneity, immunotherapy, and cellular metabolism. 2018, էջ ID 28993 |

Sargsyan M. S., Avtandilyan N. V., Karapetyan S. A.

The change of arginase activity in the serum of patients diagnosed with breast cancer | The 20th international pushchino school conference of young scientists “BIOLOGY – THE SCIENCE OF THE XXI CENTURY”. 2016, p. 167 |

Геворгян Э. Р., Автандилян Н. В., Карапетян С. А.

Изменение аргиназной активности и количества полиаминов в сыворотке крови при злокачестенных опухолях предстательной железы | 20-я Международная Пущинская школа-конференция молодых ученых «БИОЛОГИЯ - НАУКА XXI ВЕКА». 2016, стр. 174 |