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      • Chair of Civil Defense
      • Chair of Physical Education and Sports
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      • YSU STEM High School
      • YSU Ijevan Branch
    • Scientific Centers and Laboratories
      • American Studies Center
      • Center for Mathematical and Applied Research
      • Institute for Armenian Studies
      • Institute for Social and Humanitarian Studies
      • Research Center for Chemistry
      • Research Institute of Biology
      • Research Institute of Physics
      • Research Center for the Institute of Pharmacy
    • Scientific and Educational Centers
      • Observatory
      • Scientific and Educational Center for Control and Monitoring of the Quality of Medicines
      • Specialized cabinet-laboratory for the Design of Very Large Integrated Circuits (Synopsis)
      • Legal Clinic
      • Center for Applied Psychology
      • Research Center-Library of Greek Studies
      • Innovation Center for Microbial Biotechnology and Biofuels
      • Russian Center
      • Center for Russian Studies
      • Distance Learning Laboratory of Sociology
    • Column Wrapper
      • Banner
    • Administrative Divisions of YSU
      • Academic Secretary
      • Center for Doctoral Education
      • General Division
      • YSU History Museum
      • Department of Energy System Operation
      • Financial Analysis Department
      • Human Resources Department
      • Center for Admissions and Affairs with Applicants
      • Vehicle Fleet
      • Business Incubator
      • Byurakan Industrial Practice Base
      • Medical Center
      • Science Policy Department
      • Procurement Planning Department
      • Dilijan Sports and Health Center
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      • International Cooperation Office
      • Tsaghkadzor training and production base
      • Cultural Center
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      • Accounting Department
      • Center for Quality Assurance
      • Department for Special Affairs
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      • Student Dormitory
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      • Marie and Sarkis Izmirlian Library
      • Center for Strategic Planning
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  1. Main
  2. Employees
  3. Nikolay Vladimir Avtandilyan
download PDF
45-25
nv.avtandilyan@ysu.am
Nikolay
Vladimir
Avtandilyan
Research Institute of Biology
Basic and Pathological Biochemistry Laboratory
Head of laboratory

Personal information

Date of birth
1987
Scientific interests
  • Biochemistry, Medical biochemistry, Molecular biology, Animal model, Experimental biology, Experimental pathology
Education
Institution
Yerevan State University
Faculty
Faculty of Biology/Department of Biochemistry
Date
2008 - 2010
Degree name
Masters
Institution
Yerevan State University
Faculty
Faculty of Biology/Department of Biochemistry
Date
2004 - 2008
Degree name
Bachelor
Scientific Rank/degree
Institution
Yerevan State University
Date
2013
Degree name
Candidate
Specialty
Biological sciences
Scientific Supervisor
Դավթյան Միսակ Արշամի
Research Topic
Ուրեոթելիկ և ոչ ուրեոթելիկ արգինազների դերը պոլիամինների կենսասինթեզում
Language skills
English
Русский
Work experience
Institution
Yerevan State University
Period of time
2022 till now
Rank/degree
Head of The Laboratory of Basic and Pathological Biochemistry, Institute of Biology
Membership
Institution
European Association for Cancer Research
Period of time
2021 till now
Institution
Federation of European Biochemical Societies (FEBS)
Period of time
2010 till now

Publications

- Կատեգորիա -
Article
Characterization and antibacterial/cytotoxic activity of silver nanoparticles synthesized from Dicranum scoparium moss extracts growing in Armenia
Gayane Semerjyan
Inesa Semerjyan
Mikayel Ginovyan
Nikolay Avtandilyan
AIMS Biophysics
2025
29−42
Article
Tissue remodeling during high-altitude pulmonary edema in rats: Biochemical and histomorphological analysis
Ruzanna A. Shushanyan
Hasmik M. Karapetyan
Edita E. Nadiryan
Nikolay V. Avtandilyan
Anna V. Grigoryan
Anna F. Karapetyan
Tissue and Cell
2025
102727
Article
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L-arginine
Mikayel Ginovyan
Hayarpi Javrushyan
Hasmik Karapetyan
Izabela Koss‐Mikołajczyk
Barbara Kusznierewicz
Anna Grigoryan
Alina Maloyan
Agnieszka Bartoszek
Nikolay Avtandilyan
Cell Biochemistry and Function
2024
1-21
Article
The role of oxidative stress and neuroinflammatory mediators in the pathogenesis of high-altitude cerebral edema in rats
Ruzanna A. Shushanyan
Nikolay V. Avtandilyan
Anna V. Grigoryan
Anna F. Karapetyan
Respiratory Physiology and Neurobiology
2024
104286
Article
5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches
Mikayel Ginovyan
Hayarpi Javrushyan
Svetlana Hovhannisyan
Edita Nadiryan
Gohar Sevoyan
Tigran Harutyunyan
Smbat Gevorgyan
Zaruhi Karabekian
Alina Maloyan
Nikolay Avtandilyan
Scientific Reports
2024
1-16
Article
THEREGULATION OF DEAMINATION OF ADENINE COMPOUNDS IN BREASTANDLIVERIN DMBA-INDUCED BREASTCANCERRATS TREATED BYHYPERICUM ALPESTRE
G. H. PETROSYAN
S. V. MARUTYAN
N. V. AVTANDILYAN
Proceedings of the YSU B: Chemical and Biological Sciences
2024
17-26
Article
RABBITS ARGINASE I AND II: ACTIVITY AND pH SENSITIVITY OF SELF-FORMATION POLYPEPTIDES
S. M. HOVHANNISYAN
E. K. BARSEGHYAN
N. V. AVTANDILYAN
Proceedings of the YSU B: Chemical and Biological Sciences
2024
35-43
Article
Royal Jelly–Mediated Silver Nanoparticles Show Promising Anticancer Effect on HeLa and A549 Cells Through Modulation of the VEGFa/PI3K/Akt/MMP-2 Pathway
Meri Kocharyan
Syuzan Marutyan
Edita Nadiryan
Mikayel Ginovyan
Hayarpi Javrushyan
Seda Marutyan
Nikolay Avtandilyan
Applied Organometallic Chemistry
2024
1-11
Article
Anti-cancer effect of in vivo inhibition of nitric oxide synthase in a rat model of breast cancer
Nikolay Avtandilyan
Hayarpi Javrushyan
Mikayel Ginovyan
Anna Karapetyan
Armen Trchounian
Molecular and Cellular Biochemistry
2023
261-275
Article
Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
Mikayel Ginovyan
Hayarpi Javrushyan
Gayane Petrosyan
Barbara Kusznierewicz
Izabela Koss-Mikołajczyk
Zuzanna Koziara
Monika Kuczyńska
Patrycja Jakubek
Anna Karapetyan
Naira Sahakyan
Alina Maloyan
Agnieszka Bartoszek
Nikolay Avtandilyan
International Journal of Biochemistry & Cell Biology
2023
106396
Article
Screening revealed the strong cytotoxic activity of Alchemilla smirnovii and Hypericum alpestre ethanol extracts on different cancer cell lines
Mikayel Ginovyan
Svetlana Hovhannisyan
Hayarpi Javrushyan
Gohar Sevoyan
Zaruhi Karabekyan
Narine Zakaryan
Naira Sahakyan
Nikolay Avtandilyan
AIMS Biophysics
2023
12–22
Article
The Action Mechanisms, Anti-Cancer and Antibiotic-Modulation Potential of Vaccinium myrtillus L. Extract
Mikayel Ginovyan
Anush Babayan
Anahit Shirvanyan
Alvard Minasyan
Meri Qocharyan
Barbara Kusznierewicz
Izabela Koss-Mikołajczyk
Nikolay Avtandilyan
Anne Vejux
Agnieszka Bartoszek
Naira Sahakyan
Discovery Medicine
2023
590-611
Article
The possible anti-inflammatory properties of hydro-ethanolic extract of Oregano
Armenuhi Moghrovyan
Mikayel Ginovyan
Nikolay Avtandilyan
Lilya Parseghyan
Armen Voskanyan
Naira Sahakyan
Anna Darbinyan
Functional Foods in Health and Disease
2023
476-486
Article
THE CYTOTOXIC PROPERTIES OF ALCHEMILLA SMIRNOVII EXTRACT ON THE HELA CANCER CELLS VIA DOWNREGULATION OF ARGINASE ACTIVITY
S.M. Hovhannisyan
E.E. Nadiryan
M.V. Qocharyan
G.H. Petrosyan
G.P. Sevoyan
Z.I. Karabekyan
H.G. Javrushyan
M.M Ginovyan
N.V. Avtandilyan
ԵՊՀ գիտական տեղեկագիր. Քիմիա և կենսաբանություն:
2023
238-247
Article
REGULATORY EFFECTS OF RUMEX OBTUSIFOLIUS AND HYPERICUM ALPESTRE EXTRACTS ON THE QUANTITY OF IL-2 IN IN VITRO AND IN VIVO CANCER MODELS
E.E. Nadiryan
S.M. Hovhannisyan
M. V. Qocharyan
G.H. Petrosyan
H.G. Javrushyan
M.M. Ginovyan
N.V. Avtandilyan
ԵՊՀ գիտական տեղեկագիր. Քիմիա և կենսաբանություն:
2023
248-257
Article
ALTERATION OF TOTAL AND MITOCHONDRIAL ATPASE ACTIVITY IN THE BREAST AND LIVER IN BREAST CANCER-INDUCED RATS
Seda V. Marutyan
Gayane A. Petrosyan
Anna R. Muradyan
Lilit A. Marutyan
Syuzan A. Marutyan
Nikolay V. Avtandilyan
Proceedings of the YSU B: Chemical and Biological Sciences
2022
151-160
Article
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats
Hayarpi Javrushyan
Edita Nadiryan
Anna Grigoryan
Nikolay Avtandilyan
Alina Maloyan
Experimental and Molecular Pathology
2022
104763
Article
EVALUATION OF THE ANTIOXIDANT ACTIVITY AND THEANTI-CANCER PROPERTIES OFALCHEMILLA SMIRNOVII JUZ. EXTRACTON THE HELA CANCER CELL LINE
S. Hovhannisyan
E. Nadiryan
M.Qocharyan
G. Sevoyan
M. Ginovyan
N. Avtandilyan
СТУДЕНЧЕСКАЯ ГОДИЧНАЯ НАУЧНАЯ КОНФЕРЕНЦИЯ ЯРОССИЙСКО-АРМЯНСКИЙ УНИВЕРСИТЕТA
2022
40-46
Article
The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats
Hayarpi Javrushyan
Nikolay Avtandilyan
Armen Trchounian
Respiratory Physiology and Neurobiology
2021
103598
Article
NEW THERAPEUTIC APPROACHES IN BREAST ANTICANCER TREATMENT USING ARMENIAN HERBAL EXTRACTS
H.G. JAVRUSHYAN
N.V. AVTANDILYAN
M.M. GINOVYAN
A.H. TRCHOUNIAN
Biological Journal of Armenia
2021
32-38

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