Scientific interests
- Biochemistry of cancer, biochemical mechanisms of hypoxia, biochemistry of type 2 diabetes, molecular mechanisms of signaling systems, in vivo animal models, preclinical research
Education
Institution
YSU
Faculty
Biology/Biochemistry
Date
-
Degree name
Masters
Institution
YSU
Faculty
Biology/Biochemistry
Date
-
Degree name
Bachelor
Scientific Rank/degree
Institution
YSU
Date
2014
Degree name
Candidate
Specialty
Biological sciences
Scientific Supervisor
Ph.D, Professor, M.A. Davtyan
Research Topic
Influence of NO on the urea cycle
Language skills
English
Русский
Work experience
Institution
Yerevan State University
Period of time
Rank/degree
Signal Transduction and Experimental Pathology Research group leader
Institution
Yerevan State University
Period of time
Rank/degree
assistant professor
Institution
YSU
Period of time
-
Rank/degree
Research group leader
Institution
YSU
Period of time
-
Rank/degree
Junior researcher
Participation in international conferences and seminars
-
Erasmus+ Staff Training week "Implementation and Development of Erasmus+ (KA 1+2)"
Saarland University
Germany
-
Modelling immunotherapy response and toxicity in cancer” (IMMUNO-model) CA21135
Dublin City University
Ireland
Membership
Institution
The European Association for Cancer Research
Period of time
Institution
The Federation of the European Biochemical Societies
Period of time
Other information
Publications
Article
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L-arginine
Article
5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches
Article
Royal Jelly–Mediated Silver Nanoparticles Show Promising Anticancer Effect on HeLa and A549 Cells Through Modulation of the VEGFa/PI3K/Akt/MMP-2 Pathway
Article
Anti-cancer effect of in vivo inhibition of nitric oxide synthase in a rat model of breast cancer
Article
Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
Article
Screening revealed the strong cytotoxic activity of Alchemilla smirnovii and Hypericum alpestre ethanol extracts on different cancer cell lines
Article
THE CYTOTOXIC PROPERTIES OF ALCHEMILLA SMIRNOVII EXTRACT ON THE HELA CANCER CELLS VIA DOWNREGULATION OF ARGINASE ACTIVITY
Article
REGULATORY EFFECTS OF RUMEX OBTUSIFOLIUS AND HYPERICUM ALPESTRE EXTRACTS ON THE QUANTITY OF IL-2 IN IN VITRO AND IN VIVO CANCER MODELS
Article
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats
Article
The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats
Article
NEW THERAPEUTIC APPROACHES IN BREAST ANTICANCER TREATMENT USING ARMENIAN HERBAL EXTRACTS
Article
The potential therapeutic effect of NG-hydroxy-nor-L-arginine in 7,12-dimethylbenz(a)anthracene-induced breast cancer in rats
Article
NG-ՀԻԴՐՕՔՍԻ-ՆՈՐ-L-ԱՐԳԻՆԻՆԻ ՀԱԿԱՈՒՌՈՒՑՔԱՅԻՆ ԱԶԴԵՑՈՒԹՅՈՒՆԸ 7․12-ԴԻՄԵԹԻԼԲԵՆԶԱՆՏՐԱՑԵՆՈՎ ԽԹԱՆՎԱԾ ԱՌՆԵՏՆԵՐԻ ԿՐԾՔԱԳԵՂՁԻ ՔԱՂՑԿԵՂԻ ՓՈՐՁԱՐԱՐԱԿԱՆ ՄՈԴԵԼՈՒՄ
Article
The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer
Article
THE CHANGE OF POLYAMINES AND NITRIC OXIDE QUANTITIES IN HUMAN BLOOD SERUM OF PROSTATE AND BLADDER CANCER
Article
DIETHYLAMINE NONOate INFLUENCE ON RATS UREA CYCLE ENZYMES ACTIVITY AFTER AND BEFORE HYPOXIA
Article
EFFECT OF HYPOXIA ON THE ACTIVITY OF UREA CYCLE ENZYMES
Article
THE INFLUENCE OF NG -HYDROXY-L-ARGININE ON THE ACTIVITY OF THE UREA CYCLE ENZYMES
Conference
INHIBITION OF NOS ACTIVITY AS AN EFFECTIVE ANTICANCER THERAPY AGAINST 7,12-DMBA RAT MODEL OF BREAST CANCER
Conference
Arginase is an enzyme with real tricks in antitumor treatment of 7,12-dimethylbenz(a) anthracene induced breast cancer in rats
