Group on Biochemistry of Drug Effects
The scientific group on Biochemistry of Drug Effects is engaged in the study of the biochemical mechanisms of the effects of various drugs (including anticancer and anti-inflammatory) in the nuclei of the liver, thymus, lung, kidney, brain, breast, and pancreas tissues of rats of different sexes and ages, as well as in blood and plasma cells. The goals and objectives of the scientific group's research are:
To study the specifics of the effects of drugs on the activity of the nuclear enzyme PARP 1, the degree of chromatin packaging, and the quantitative content of NAD+ in the nuclei of the corresponding tissues of both healthy, cancer, and diabetic (hyperglycemic) rats.
To investigate the patterns associated with the separate and combined effects of anticancer drugs and various steroids on the activity of some antioxidant enzymes, determination of the amount of glutathione after separate and combined effects of anticancer drugs and various steroids, and the characteristics of the activity of the antioxidant enzyme glutathione peroxidase in the blood plasma and various tissues of rats.
Group members:
